Cochrane produces systematic reviews which are recognized as the highest standard in evidence-based health care resources. Listen to Cochrane review authors explain in plain language the evidence and findings of their high-impact reviews. In 5 minutes or less, healthcare professionals to patients and families can understand the latest trusted evidence to help make better informed decisions.
Diffuse large B-cell lymphoma is a fast-growing cancer of the lymphatic system. A new Cochrane Review from September 2021 looks at the evidence on the effects of one treatment, chimeric antigen receptor (CAR) T-cell therapy for people whose disease relapses or does not respond to other treatments. We asked the lead author, Moritz Ernst from the Faculty of Medicine and University Hospital Cologne in Germany to tell us what they found.
4 min 33 sec
There are many Cochrane Reviews of ways to help smokers to quit. One of these, on research into interventions that might help in reducing any subsequent weight gain was updated in October 2021. Annika Theodoulou from the University of Oxford in the UK worked on the update and tells us what they found in this podcast.
4 min 14 sec
Music therapy is used for a variety of conditions and several Cochrane Reviews examine its effects. A team of music therapists with expertise in the use of music therapy with medical patients updated their review for cancer patients in October 2021. Joke Bradt from the department of Creative Arts Therapies at Drexel University in Philadelphia, USA tells us what they found in this Evidence Pod. She conducted the review with Cheryl Dileo from Temple University in Philadelphia, Katherine Myers-Coffman from Molloy College in Rockville Center, and Jacelyn Biondo, postdoctoral fellow in the department of Creative Arts Therapies at Drexel University.
6 min 50 sec
Chronic low back pain is a very common health problem and there are many relevant reviews in the Cochrane Library. A new review, of nearly 250 studies of the effects of exercise, was added to the Library in September 2021. Toby Lasserson, Deputy Editor in Chief of the Library spoke with lead author, Jill Hayden from Dalhousie University in Halifax, Canada about the review and its findings.
5 min 50 sec
Cochrane is producing a series of living reviews relevant to the COVID-19 pandemic and, in August 2021, we published the first version of our review on remdesivir. We asked one of the authors, Felicitas Grundeis from the University of Leipzig Medical Center in Germany to tell us about the need for the review and its results.
3 min 25 sec
Cochrane is producing a series of reviews to help decision makers respond to the COVID-19 pandemic. In September 2021, we published the first version of a Living Systematic Review on the effects of monoclonal antibodies for treating COVID-19 and in this podcast we speak to Nina Kreuzberger one of the lead authors, about the review, which was initiated in the Germany-wide joint projects "COVIM" and "CEOsys" and funded by the Federal Ministry of Education and Research of Germany.
4 min 49 sec
Cochrane is producing a series of reviews relevant to the COVID-19 pandemic. In July 2021, we published the first version of our review on the effects of ivermectin for the prevention and treatment of COVID-19, in a collaboration between Cochrane's Infectious Diseases and Haematological Malignancy Groups. We asked one of the authors, Maria Popp from University Hospital Wuerzburg in Germany, to tell us about their findings.
4 min 40 sec
The Cochrane Common Mental Disorders Group has produced many reviews of the effects on interventions for conditions such as anxiety and depression. They added to these in November 2020 with a substantially revised version of their review of the use of cognitive behavioural therapy for children and adolescents. We asked one of the authors, Tessa Reardon from the University of Oxford in the UK, to tell us about the importance of this review and what it found.
4 min 49 sec
Cochrane Reviews cover a wide range of interventions to help couples with infertility or subfertility to conceive, and these are updated to take account of new evidence or introduce new review methods. One of the reviews, looking at preconception lifestyle advice for people with infertility, was updated for the first time in April 2021 and we asked lead author, Tessy Boedt from the Department of Chronic Diseases and Metabolism at KU Leuven in Belgium to tell us more.
4 min 16 sec
Cochrane is producing a series of reviews to help decision makers respond to the COVID-19 pandemic. In May 2021, we published the first version of a living systematic review on the effects of vitamin D supplementation and, in this podcast, Vanessa Piechotta talks to the first author and her colleague at the University Hospital in Cologne Germany, Julia Stroehlein, about the potential effects of vitamin D and the evidence they’ve found.
5 min 26 sec
Some Cochrane reviews investigate the effects of different ways of stopping, rather than starting treatments. A new review in April 2021 does this for adults who have been taking antidepressants for some time. One of the authors, Mieke van Driel from The University of Queensland in Australia tells us more in this podcast.
5 min 7 sec
In March 2021, the Cochrane Neuro-Oncology Group published a series of eight new complex systematic reviews on priority topics for the brain tumour community. These were selected from the most important unanswered questions identified by people in this area using James Lind Alliance Priority Setting Partnership methods, which bring together patients and the public with practitioners. One of the reviews was a network meta-analysis of treatments for glioblastoma in the elderly and we asked lead author, Catherine Hanna from the University of Glasgow in the UK, to tell us about the condition and the review.
5 min 16 sec
Many healthcare organizations use electronic health records to manage patient data and it has been suggested that it may be beneficial if patients can access their own records as well. In this podcast, Christina Cannellopoulos talks with lead author Elske Ammenwerth, a researcher in Medical Informatics from the University UMIT TIROL in Austria, about their Cochrane Review on this topic.
5 min 25 sec
Cochrane is producing a series of reviews to help decision makers respond to the COVID-19 pandemic. We’re keeping these reviews up to date as new evidence emerges and are now on the fourth version of our living review of convalescent plasma and hyperimmune immunoglobulin for COVID-19 patients, which was published in May 2021. In this podcast, Vanessa Piechotta speaks with one of the lead authors, Claire Iannizzi both from the University Hospital Cologne in Germany about the latest findings.
6 min 53 sec
Postnatal depression affects many women in the months after having their baby and one of the early Cochrane Reviews looked at its treatment with antidepressants. The very first version of the review was published in 2001, and the review has been refreshed and updated again, with a new version published in February 2021. Here’s one of the authors, Claire Wilson from King’s College London in the UK, to tell us more.
4 min 24 sec
Infectious diarrhoea is responsible for many thousands of deaths every day around the world and probiotics have been suggested as a possible treatment. The relevant Cochrane Review was updated for the second time in December 2020 and first author, Shelui Collinson from the Liverpool School of Tropical Medicine in the UK describes the latest findings in this podcast.
4 min 45 sec
In March 2021, the Cochrane Neuro-Oncology Group published a series of eight new systematic reviews on priority topics for the brain tumour community. These were selected from the most important unanswered questions identified by patients, the public and practitioners. In this podcast, Kathreena Kurian from the University of Bristol in the UK tells us about one of the reviews, which looked at the evidence on tests that might help to predict survival in patients who have received chemotherapy for glioblastoma.
3 min 24 sec
The Cochrane Pregnancy and Childbirth Group has done many reviews of interventions that might prevent stillbirth and, in December 2020, they brought these together in an overview. In this podcast, one of the Group’s researchers, Dell Horey, talks with lead author Erika Ota, a professor at the St. Luke’s International University in Japan, about the findings.
5 min 56 sec
As well as examining the evidence for starting patients on drug treatments, Cochrane Reviews also look at the relative benefits of stopping or continuing once someone has started taking them. This is the case with a February 2021 review of the effects of withdrawing or continuing two common classes of drug treatment for people with dementia. We asked lead author, Carole Parsons from Queen’s University Belfast in Northern Ireland to tell us what they found.
5 min 21 sec
The Cochrane Anaesthesia Group has produced a wide variety of reviews relevant to procedures related to surgery. One of these looks at the use of melatonin for preoperative and postoperative anxiety in adults and it was updated in December 2020. We asked the new lead author, Bennedikte Madsen, from the Center for Perioperative Optimizationin Herlev Hospital in Denmark to tell us about the latest findings.
3 min 31 sec
There are many Cochrane reviews about the management of patients in intensive care units, covering a wide range of interventions, and the second update of one of these, in December 2020, brought together the latest evidence on the effects of oral hygiene care. Here’s the lead author, Fang Hua from Wuhan University in China to tell us about the latest findings.
3 min 36 sec
Cochrane has already produced many rapid reviews to help decision makers with their response to the COVID-19 pandemic and we are updating these to try to keep up with the accumulating evidence. In this podcast, lead author, Jake Burns from the University of Munich in Germany describes the latest findings of our review of the effects of control measures for international travel, which was updated in March 2021.
3 min 59 sec
Many millions of people suffer from respiratory diseases such as chronic obstructive pulmonary disease, interstitial lung disease and bronchiectasis; and there are Cochrane Reviews for a wide range of interventions that might help, including drugs, devices and physical therapies. These were added to in January 2021 with a new review of the effects of providing pulmonary rehabilitation remotely and we asked the lead author, Narelle Cox from Monash University in Melbourne Australia, to tell us more in this podcast.
3 min 48 sec
Alongside the hundreds of Cochrane Reviews of treatments for patients with cancer, there are many of ways to reduce the adverse effects of those treatments. In December 2020, we published the third update of one of these, looking at the effects of drugs to prevent venous thromboembolism in patients receiving chemotherapy. Marcello Di Nisio from the University "G. D'Annunzio" of Chieti-Pescara in Italy tells us about the latest findings in this podcast.
4 min 24 sec
The Cochrane Library contains more than 140 Cochrane Reviews of the accuracy of diagnostic tests, covering a very wide range of conditions. One of these reviews, on a test used to detect tuberculosis in the lungs, was updated for the third time in February 2021 and Karen Steingart from the Liverpool School of Tropical Medicine in the UK speaks with first author, Jerry Zifodya from Tulane University in New Orleans, USA about the latest findings in this podcast. This review is also included in the Cochrane Library Special Collection for World Tuberculosis Day on 'Diagnosing tuberculosis'.
6 min 40 sec
Our programme of rapid reviews for COVID-19 covers both the diagnosis and treatment of the disease and the reviews are being updated as new evidence becomes available. Among these is a review on imaging tests for diagnosing the condition, and we asked the lead author of the March 2021 update, Nayaar Islam from The Ottawa Hospital Research Institute in Canada, to describe the latest findings in this podcast.
4 min 26 sec
The Cochrane Neonatal Group has produced more than 400 Cochrane Reviews over the last two decades, updating these periodically as new evidence becomes available. In March 2021, they published the update of their review of opioids for newborn babies requiring mechanical ventilation and we asked two co-authors of the review, Olga Romantsik and Matteo Bruschettini from Skåne University Hospital in Lund, Sweden, to tell us about the latest findings.
5 min 35 sec
Within our growing collection of reviews relevant to COVID-19, we have several relating to its diagnosis. One of these, on the use of rapid point-of-care tests was updated in March 2021. Here's lead author Jacqueline Dinnes from the University of Birmingham in the UK to tell us what they found for antigen tests.
4 min 37 sec
The Cochrane Pain, Palliative and Supportive Care Group has more than 250 active reviews of the effects of a wide range of interventions. These were added to in October 2020 by a new review of the effects of using virtual reality to distract children undergoing painful procedures. We asked lead author, Veronica Lambert from Dublin City University in Ireland to tell us that they found.
4 min 41 sec
Endometriosis is a common problem for hundreds of millions worldwide and Cochrane has produced more than two dozen reviews of a variety of possible treatments. These are kept up to date as new evidence becomes available and, in October 2020, the review of laparoscopic surgery was updated. In this podcast, former fertility patient and patient advocate, Katy Lindemann from Uber Barrens Club, speaks with senior author, James Duffy from King’s Fertility in the UK, about the latest findings.
3 min 41 sec
We're producing a series of reviews covering the accumulating evidence on COVID-19, which are not only looking at the diagnosis and treatment of the disease but are also examining its links to other conditions. One of these reviews, on the effects of COVID-19 on cardiovascular health, was published in March 2021. In this podcast, co-author Keng Siang Lee, from the University of Bristol speaks with the first author, Pierpaolo Pellicori (photo) from the University of Glasgow in the UK about the findings.
6 min 2 sec
In March 2021, the Cochrane Neuro-Oncology Group published a series of eight new systematic reviews on priority topics for the brain tumour community. These were selected from the most important unanswered questions identified by people in this area, using James Lind Alliance Priority Setting Partnership methods, which bring together patients and the public with practitioners. In this podcast, one of the Group’s consumer representatives, Helen Bulbeck, talks with lead author Robin Grant, a consultant neurologist involved in the Edinburgh Centre for Neuro-Oncology in the UK, which is one of the Tessa Jowell Brain Cancer Mission Centres of Excellence, about the recent review of interventions to reduce time to diagnosis of brain tumours.
7 min 50 sec
In March 2021, the Cochrane Neuro-Oncology Group published a series of eight new complex systematic reviews on priority topics for the brain tumour community. These were selected from the most important unanswered questions identified by people in this area using James Lind Alliance Priority Setting Partnership methods, which bring together patients and the public with practitioners. In this podcast, one of the Group’s consumer representatives, Helen Bulbeck, talks with author Robin Grant, a consultant neurologist involved in the Edinburgh Centre for Neuro-Oncology in the UK about the review of the long-term neurocognitive and other side effects of using radiotherapy as a treatment for glioma.
7 min 43 sec
Alongside its many reviews of interventions to help people quit smoking, the Cochrane Tobacco Addiction Group published a new review in March 2021 which looks at the effects of quitting smoking on mental health. Co-author, Dr Amanda Farley from the University of Birmingham in the UK tells us about the importance of the review and its findings in this podcast.
4 min 23 sec
The Cochrane Musculoskeletal Group has produced more than 200 reviews of a very wide range of interventions for patients with musculoskeletal problems. In this podcast, senior author Peter Wall, talks with Imran Ahmed, Trainee Orthopaedic Surgeon and NIHR Doctoral Researcher at Warwick Clinical Trials Unit and University Hospitals Coventry and Warwickshire NHS Trust in the UK about their December 2020 review of the effects of using a tourniquet in knee replacement surgery.
4 min 29 sec
Cochrane is preparing a special series of reviews to help decision makers deal with the COVID-19 pandemic and its impact, and we are keeping these up to date as new evidence becomes available. One of these reviews examines the accuracy of using signs and symptoms to diagnose whether someone has the disease. It was first published in June 2020 and has been updated in February 2021. Here’s the lead author, Thomas Struyf from the Katholieke Universiteit Leuven in Belgium, to tell us about the latest findings.
4 min 29 sec
More than 140 Cochrane Reviews investigate the accuracy of diagnostic tests, covering a very wide range of conditions. One of these reviews, on a test used to detect tuberculosis, was updated in January 2021. The first author, Mikashmi Kohli from McGill University in Montreal Canada, tells us about the updating of the review and what they found.
6 min 54 sec
Up to one in four couples planning a baby may have difficulty conceiving. Several interventions are available that might help and Cochrane has reviewed many of these. In August 2020, our review of antioxidants for female subfertility was updated and we asked one of the authors, Dr Rebecca Mackenzie-Proctor from the Auckland City Hospital in New Zealand to tell us about the rationale for the review and the latest evidence.
4 min 52 sec
Alongside many Cochrane reviews of treatments for people with dementia, there are some that look at the effects of interventions that might help the people who care for them. These were added to in January 2021 with a new review of interventions designed to be delivered remotely. Here’s one of the authors, Jenny McCleery from the Oxford Health NHS Trust in England, to tell us about the findings.
4 min 16 sec
One of the earliest Cochrane Reviews studied the effects of steroids for women at risk of a pre-term delivery, and built on an even earlier review. The Cochrane Review has been updated several times and the most recent version was published in December 2020. Two of the authors discuss the latest evidence in this podcast, starting with Emma McGoldrick from the Liverpool Women's NHS Foundation Trust in the UK, who’s talking with Fiona Stewart from the Department of Women's and Children's Health at The University of Liverpool.
4 min 50 sec
Many women who are breastfeeding experience breast engorgement and this can be a very distressing condition. Several possible treatments are known. The evidence for these were brought together in a third update to the relevant Cochrane Review in September 2020. The two authors, Irena Zakarija-Grković from Cochrane Croatia, based at the University of Split School of Medicine, and Fiona Stewart from the University of Liverpool in the UK talk about their findings in this podcast, starting with Fiona.
5 min 17 sec
Pine bark extract supplements are marketed to prevent or treat a wide range of chronic diseases and a Cochrane Review from September 2020 assesses the evidence on their efficacy and safety. Monika Evans spoke with lead author, Nina Robertson from Stellenbosch University in South Africa about the findings.
4 min 50 sec
Alongside the many thousands of Cochrane Reviews of the effects of interventions, our reviews of diagnostic test accuracy, or DTA, provide evidence to help clinicians choose between different techniques for diagnosing a health problem. In July 2020, we published the new DTA review on ultrasound versus x-ray for diagnosing pneumothorax in trauma patients. Here's lead author, Kenneth Chan from the Department of Emergency Medicine in the University of Calgary in Canada, to tell us what they found.
3 min 53 sec
Obstructive sleep apnoea is a sleeping disorder that stops a person's breathing for periods during the night. Several treatments have been suggested and a new Cochrane Review for one of these, myofunctional therapy, was published in November 2020. Here's Emma Dennett, Managing Editor from the Cochrane Airways Group to tell us about the condition and the therapy, and the review's findings.
3 min 13 sec
The Cochrane Neonatal Group has produced more than 400 reviews in the last 25 years and strives to keep these up to date as new research becomes available. In October 2020, they produced the third update of the review of probiotics to prevent necrotising enterocolitis in very preterm or very low birth weight infants. We asked lead author, William McGuire from the University of York in the United Kingdom, to tell us about the latest evidence.
5 min 47 sec
At the start of the COVID-19 pandemic, we gathered the most important questions from a range of stakeholders, including clinicians, patients and researchers. These led to a string of new reviews during 2020 and one of these, published in November 2020, looks at interventions to support the resilience and mental health of frontline workers. Here’s Alex Pollock from Glasgow Caledonian University in Scotland to tell us about the review.
4 min 17 sec
The COVID-19 pandemic is creating challenges for diagnosis of the disease, as well as for its treatment. The rapid reviews being prepared and updated by Cochrane are covering both areas. We asked the lead author of the November 2020 versions of our review of the evidence on using imaging tests to diagnose the condition, Nayaar Islam from The Ottawa Hospital Research Institute in Canada, to describe the latest findings in this podcast.
4 min 35 sec
The Cochrane Gynaecology and Fertility Group has produced more than 80 reviews on assisted reproduction and continues to add to these. In July 2020, they added a new review on the use of growth-factor supplemented culture media and we asked the lead author, Sarah Armstrong from the University of Sheffield in the UK to tell us what they found.
4 min 12 sec
Chronic pain is a major problem for many people, and it’s important to have up-to-date evidence on the effects of possible treatments. With that in mind, we published the third update of the Cochrane Review of psychological therapies for chronic pain in August 2020 and here’s lead author, Amanda Williams from University College London in the UK to tell us about the latest findings.
4 min 21 sec
Renal vasculitis causes damage to the small blood vessels inside the kidneys and - when untreated - can lead to a rapid loss of kidney function. Therapies that block the immune system to switch off the vasculitis process are available but can lead to serious infections and other long-term complications. The Cochrane Review of treatments to induce and maintain disease remission for renal vasculitis was updated in January 2020 and we asked lead author, Giles Walters from Canberra Hospital in Australia to bring us up-to-date with the findings.
5 min 54 sec