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CRISPR: A Crack in Creation

By The Aspen Institute

CRISPR is the cheapest, simplest, and most effective way of manipulating DNA. It has the power to give us the cure to HIV, genetic diseases, and some cancers. It could even help address the world’s hunger crisis. But, it may result in unforeseen consequences. The technology could lead to intentionally mutating embryos to create “better” humans. Jennifer Doudna, whose research helped create CRISPR, speaks with Aspen Institute President Walter Isaacson about the latest technological developments in gene editing and the unthinkable power to control evolution. Doudna wrote the book A Crack in Creation: Gene Editing and the Unthinkable Power to Control Evolution with her fellow researcher Samuel Sternberg. This week’s recommended companion episode is “Should We Design Our Babies?.” Find it here. Follow the show on Twitter @aspenideas and Facebook at Email your comments to

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