Named after the character Margot Tenenbaum in the Wes Anderson arthouse comedy The Royal Tenenbaums, his group, which consisted of the Indianapolis native and a rotating lineup, released its debut, The Dust of Retreat, on local label Standard Recording
in 2005. It was critically well-received, and Epic
issued the label-approved follow-up Not Animal (alongside the band's preferred version, Animal!) in 2007. Edwards parted ways with Epic
and relocated to Chicago for 2010's leaner Buzzard, and 2012's Rot Gut, Domestic explored more guitar-driven '90s-styled rock, also flirting with country & western influences. Margot & the Nuclear So and So's
' fifth LP, 2014's Sling Shot to Heaven, was recorded in a home studio and released on their own label. Edwards then signed with Indianapolis-based Joyful Noise Recordings
, which put out a 2015 collection of over 50 previously unreleased songs, demos, and alternate takes from Margot
titled Bride on the Boxcar: A Decade of Margot Rarities 2004-2014.