The success of the quartet's engagement with the community in Jesup brought it to the attention of the national media, and its high level of musicianship won it a 1993 Naumberg Chamber Music Award. Following the Jesup residency, the quartet went on to establish an international performing career. The Yings' collaborators have included Turtle Island String Quartet, the St. Lawrence String Quartet, Menahem Pressler, Paul Katz, and Gilbert Kalish. Based on their experience in Iowa, they have sought out unconventional venues for their concerts, including libraries, hospitals, prisons, and museums. One of their most ambitious projects has been "No Boundaries," a series of concerts at New York's Symphony Space, in which their intention was to stretch conventional expectations of a classical music concert by involving a wide variety of artists in their performance. With assistance from the Institute for American Music, they have commissioned new works by Augusta Read Thomas, Ned Rorem, Carter Pann, Chen Yi, and Bernard Rands, among others.
The breadth of the Yings' musical interests is reflected in their recordings, which include works by Tchaikovsky, Lowell Liebermann, Michael Torke, and Osvaldo Golijov. In 2006, their CD of music by Oliver Nelson, Mark Summer, David Balakrishnan, Darius Milhaud, Evan Price, Paul McCartney, and John Lennon, made in collaboration with the Turtle Island String Quartet, was awarded a Grammy as Best Classical Crossover album.
The quartet is committed to education and has had residencies at Interlochen Music Festival, Bowdoin Summer Music Festival, Brevard Music Festival, Northwestern University, and Harvard University, where it has been the Blodgett Artists-in-Residence since 2001. The Yings' primary teaching commitment has been as faculty members at the Eastman School of Music, where they also serve as Quartet-in-Residence.
In 2009, Timothy Ying left the quartet to pursue other ventures; Ayano Ninomiya became the group's first violinist in 2010.