The more mature and ambitious Heroine was issued in March 2006 to positive reviews, and the band supported its entry into the Top 40. From First to Last jumped up to the majors soon after, inking a deal with Capitol that April. As work began on new material, Moore parted ways with the group in early 2007 to concentrate on solo work (Skrillex
), and guitarist Matt Good took over lead vocal duties. Around the same time, From First to Last's deal with Capitol also fizzled. But the band was determined and pressed on with plans to record.
But by July 2010, it was decided that the band would go on an indefinite hiatus. Following three years of inactivity, FFTL reunited in November 2013. A newly expanded six-man lineup released the group's fifth album, Dead Trees, on Sumerian Records.
In January 2017, Moore made a surprise return to the band, and they released the single "Make War."