As a soloist and chamber musician she has given concerts worldwide and collaborated with Heinz Holliger, Gerhard Oppitz, the conductors Andrey Boreyko, Michael Sanderling, Gürer Aykal and John Storgårds, the Berlin Radio Symphony Orchestra, the Mozarteum Orchestra Salzburg , the HR-Symphony Orchestra, the Dresden Philharmonic, the Bern Symphony Orchestra, the Essen Philharmonic Orchestra, the Heidelberg Symphonic Orchestra and ACME, the American Contemporary Music Ensemble.
In 2012, Carolina played the theremin solo at the world premiere of the two symphonies “Mesopotamia” and “Universe” by Fazil Say. The Finnish composer Kalevi Aho dedicated a theremin concert to Carolina which she performed for the first time in October 2012. This Concerto was published by BIS Records in July 2014. The recording was rewarded in 2015 with the german ECHO-Classic prize in the category "Concert Recording of the Year (Music 20./21. century)".
Together with the pianist and composer Christopher Tarnow, she is forming a duo since 2013. Their works have been published in October 2015 by the label GENUIN. In 2016 Carolina Eyck and American Contemporary Music Ensemble (ACME) released the "Fantasias for Theremin and String Quartet", composed by Carolina Eyck.