A native of East St. Louis, IL, Wilson fell in love with music as a child, listening to a mixture of classic soul, jazz, and gospel. She started singing in her church's choir as a kid, and as an adult she began her professional career as a backup singer and featured vocalist with Donald Lawrence & Company.
Wilson first gained attention during her tenure with the Donald Lawrence & Co., when she had a solo on "Happy Being Me." After independently recording her first album Worship Soul in 2010, she signed a license deal with then EMI Gospel, which released Worship Soul in 2012. Thanks in part to the gospel hit singles "Speechless" and "Jesus Will," Worship Soul became a success, earning crossover attention from Ben Ratliff, a New York Times critic who put the album on his Best of 2012 list. Worship Soul garnered her first Grammy nomination for Best Gospel Album. In 2014 she released Vintage Worship, which was anchored by the single "That's What He's Done for Me" and wound up earning Wilson another Grammy nomination for Best Gospel Album. In 2017, Wilson released her 3rd Album Grammy Nominated Album Sunday Song on her label Reflection Media, Inc.