DeLisle moved to Los Angeles while still in her teens, where she began working a little in theater, even trying a standup comedy routine, where her natural ability to do voice impressions came to the fore. Soon she was picking up voice acting jobs, and her personal "voiceography" is a lengthy one, including roles in The Fairly OddParents, The Powerpuff Girls, Rugrats, Grim & Evil, Dexter's Laboratory, and many other animated movies and shows. She never gave up on her music, though, and was a member of the all-girl cowpunk band Side Saddle in the late '90s. She formed her own independent label, Hummin'bird Records, and released three albums, The Small Time in 2000, the live set Bootlegger, Vol. 1 in 2003, and Homewrecker in 2004.
Gradually she developed a sparse, literate neo-Appalachian style, which sounded a bit like a weary and goth-haunted Dolly Parton, and it led to her signing with Sugar Hill Records, which released Graceful Ghost in 2004 and Iron Flowers in 2005. She married guitarist Murry Hammond (a member of the band Old 97's) in 2002, and their courtship and wedding were featured on an episode of The Learning Channel series A Wedding Story. ~ Steve Leggett, Rovi