Raksin remained with Harms/Chappell until 1935, when he relocated to Hollywood to work with the legendary Charlie Chaplin on Modern Times, arranging the film's score based on melodies Chaplin would hum or whistle. He briefly returned to Philadelphia long enough to assist conductor Leopold Stokowski in premiering his concert piece "Montage" before returning to Hollywood full-time -- in 1937 alone, Raksin racked up no fewer than 11 different film credits, and he would maintain a frenetic pace for decades to follow. He authored his first true classic in 1944: Commissioned to score Otto Preminger's atmospheric murder mystery Laura, Raksin composed the film's haunting theme just days after separating from his first wife, drawing on her "Dear John" letter for inspiration and channeling his heartbreak into one of the most memorable and recognizable melodies in motion picture history. Johnny Mercer later added lyrics, and "Laura" is now recognized as an American standard, recorded by Frank Sinatra, Rosemary Clooney, Ella Fitzgerald, and countless others.
Raksin earned his first Academy Award nomination in 1947 for his work on the period drama Forever Amber; he earned his only other Oscar bid 11 years later for Separate Tables, never taking home a statuette. He nevertheless worked on some of the most celebrated motion pictures of the postwar era, among them Abraham Polonsky's Force of Evil, Nicholas Ray's Bigger Than Life, and Vincente Minnelli's The Bad and the Beautiful -- in all, Raksin scored in excess of 100 films, not to mention themes and scores for more than 300 television programs including Ben Casey and Life With Father. He also worked in radio, most notably writing, narrating, and conducting interviews for a three-year series of 64 hour-long programs entitled The Subject Is Film Music, and from 1956 until his death, he taught film composition at the University of Southern California. Raksin's film and television output slowed during the 1970s, and in 1983 he completed his last major celluloid score for the landmark telefilm The Day After; soon after he received a commission from the Library of Congress, premiering his choral work "Oedipus Memneitai (Oedipus Remembers)" on October 30, 1986. Raksin died at his Van Nuys, California home on August 9, 2004 at the age of 92.