His first album Improvisiones (2005) introduced him to the jazz scene as a composer making music in a very personal way. "Sanguinetti pushes forth toward a new jazz genre", according to All About Jazz.
He has made a lot of music for contemporary dance works. Some of those projects are included in albums Los Procesos de Franz (2008) and El Otro (2011). Albums Ocho (2013) and 9 (2017) show Sanguinetti's most inspired musical atmospheres and well produced by Mariano Esaín. Both albums were nominated for the Latin Grammy Awards (in the Packaging Design category).
His 2016 album Cómo Desaparecer Completamente (versions on Radiohead's music) was included in the Best of the Year by journalist Geno Thackara (USA) for www.allaboutjazz.com. Two tracks from that project were selected to be part of the french compilation: Radiohead in Jazz (A Jazz Tribute to Radiohead). Sanguinetti was opening act for The Bad Plus (2014) and Battles (2019) in their shows in Argentina. In both 2016 and 2017, he was awarded: Best Musician, Best Pianist and Best Composer of the year by the Argentinean press.
New release Inmoral (2019) includes versions on Gustavo Cerati's music, produced by Tweety González (Soda Stereo's keyboards player and Cerati's producer).