Nanne began her career as a solo artist in 1998 when she entered Melodifestivalen again with "Avundsjuk," a self-penned song about jealousy between women (the title translates as "Envious"). For her performance of the song, Nanne donned a purple wig and a pair of prosthetic ears very similar to those of Star Trek's Mr. Spock. The song came in fourth, and went on to reach number six in the Swedish charts, her first hit as a solo performer. Her debut solo album, Cirkus Homo Sapiens, followed. A second solo album, 2001's Alla Mina Ansikten, was a commercial failure. That same year, she competed to represent the U.K. in its Eurovision heats with "Men," but finished in last place. She returned to Melodifestivalen in 2003 with "Evig Karlek," a mix of dance music and operatic vocals, but failed to qualify for the grand final.
In 2005 she entered Melodifestivalen yet again with "Häll Om Mig," a driving, tribal song about the need to be sexually close to somebody. The song easily qualified for the final and was considered a favorite for victory. Controversially, she won overwhelmingly on public votes, but after being placed third by the jury she finished second overall, to Martin Stenmarck with the song "Las Vegas." However, Nanne's song went on to be a far bigger hit, topping the Swedish charts for two weeks and remaining in the charts for over six months. Her album Altid Pa Vag became the best-selling album of her career, and yielded a further three Top 20 hits in the Swedish singles charts, "Om Du Var Min," "Lyckos Dig," and "Många Karlar Lite Tid." The year also saw the release of a greatest-hits compilation, 20 år med Nanne, which covered her time with One More Time and Sound of Music in addition to her solo recordings. In 2006 Nanne announced that she had been diagnosed with breast cancer and was forced to cancel all promotional engagements. She was given the all-clear and returned in 2007 with her fourth solo album, Jag Måste Kyssa Dig. ~ John Lucas, Rovi