At 12, Deodato started to learn the accordion. Two years later he began his studies on piano, orchestration, arrangement, and conducting, and started playing in dances and nightclubs. In 1959, he became a member of Roberto Menescal's and Durval Ferreira's groups, playing bossa nova. His earliest compositions are from that period. In 1962 he formed his first group, which had Roberto Menescal as a member. Leaving the group, Deodato started to write arrangements for Odeon as a freelancer, having worked in the earliest albums by Wilson Simonal and Marcos Valle. In 1964 he did the arrangements and conduction of the LP Inútil Paisagem and recorded the LP Os Gatos. With Os Catedráticos, Deodato recorded the LPs Impulso! Samba (1964), Tremendão (1964), and Ataque, which contained his compositions "Ataque" and "Razão de Viver" (with Paulo Sérgio Valle). He was a member of the committee that selected the compositions to be presented in the earliest editions of the historic FIC (International Song Festival). Having selected three songs by Milton Nascimento for the II FIC (1967), he is considered to having being responsible for the launching of the songwriter.
In 1967 he moved to New York, NY, to write arrangements for the Luiz Bonfá album with Maria Helena Toledo. When writing the arrangements for Astrud Gilberto's Beach Samba, he became acquainted with Creed Taylor, who hired him to arrange for other CTI's artists, like Tony Bennett, Frank Sinatra, Roberta Flack, Paul Desmond, Tom Jobim, Walter Wanderley, and Aretha Franklin. Deodato worked also in that period with Ray Bryant. In 1969, he released the classic LP Donato/Deodato with João Donato. His arrangement for "Also Sprach Zarathustra" (Richard Strauss), written in 1973, was included in the soundtrack of Stanley Kubrick's 2001 and on Deodato's album Prelude, which sold five million copies, being awarded by Billboard, Cashbox, Record World, and Playboy magazines, also winning a Grammy in the Best Instrumental Pop/Rock performance. Having played at the Hollywood Bowl with the CTI All-Stars Band, he formed his own group that opened at New York's Madison Square in 1973. After many years touring, arranging, and producing intensively, and releasing many individual albums, Deodato worked with Björk, arranging her albums Post, Telegram, and Homogenic. Also in the 1990s, he worked with the Brazilian artists Gal Costa, Titãs (Vol. II), and Carlinhos Brown (Omelete Man). In 2000, Deodato wrote the arrangements for the soundtrack of Bruno Barreto's film Bossa Nova. ~ Alvaro Neder, Rovi